OAS3 Antibody, Biotin conjugated

Спецификация

Объем	50 мкг
Синонимы	2'-5'-oligoadenylate synthase 3 ((2-5')oligo(A) synthase 3) (2-5A synthase 3) (EC 2.7.7.84) (p100 OAS) (p100OAS), OAS3
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q9Y6K5
Иммуноген	Recombinant Human 2'-5'-oligoadenylate synthase 3 protein (424-565AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L. Displays antiviral activity against Chikungunya virus (CHIKV), Dengue virus, Sindbis virus (SINV) and Semliki forest virus (SFV).
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Biotin
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	2'-5'-oligoadenylate synthase 3
Области исследований	Epigenetics and Nuclear Signaling, Immunology
Ссылка на страницу на сайте производителя	ссылка

Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	50 мкг
	Кат. номер:	CSB-PA897591LD01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: OAS3 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке).