NRG1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Pro-neuregulin-1, membrane-bound isoform, Pro-NRG1, NRG1, GGF | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q15491 | | Иммуноген | Synthesized peptide derived from human NRG1 isoform-10. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | The protein encoded by this gene is a membrane glycoprotein that that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).<br/><br/>Xiao-Feng Le, Cancer Res., Jul 2000, 60: 3522 - 3531.<br/>Samuel D. H. Chan, J. Biol. Chem., Sep 1995, 270: 22608.<br/>Daniel C. Gamett, J. Biol. Chem., Aug 1995, 270: 19022.<br/>Mohammed Rahmatullah, Mol. Cell. Biol., Nov 1998, 18: 6245 - 6252.<br/><br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Neuroscience,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from SKOV3 cells, using NRG1 isoform-10 antibody.
 | Immunohistochemical analysis of paraffin-embedded human brain tissue using NRG1 isoform-10 antibody.
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Наименование: NRG1 Antibody.