NCAM1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | MSK39, NCAM1, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P13591 | | Иммуноген | Peptide sequence around aa.850~854(Q-T-K-E-N)derived from Human CD56(NCAM). | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | NCAM (neural cell adhesion molecule, CD56) is an adhesion glycoprotein with five extracellular immunoglobulin-like domains followed by two fibronectin type III repeats. Structural diversity is introduced by alternative splicing resulting in different cytoplasmic domains (1). NCAM mediates neuronal attachment, neurite extension and cell-cell interactions through homo and heterophilic interactions. PSA (polysialic acid) post-translationally modifies NCAM and increases the metastatic potential of small cell lung carcinoma, Wilms+ tumor, neuroblastoma and rhabdomyosarcoma (2). CD56 and CD16 are commonly used to identify NK cells although some cells with the T cell markers CD3 and CD4 also express CD56 (3).<br/><br/>Cunningham, B. A. et al. (1987) Science 236, 799-806. <br/>Seidenfaden, R. et al. (2003) Mol. Cell. Biol. 23, 5908-5918. <br/>Robertson, M.J. and Ritz, J. (1990) Blood 76, 2421-2438. <br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Neuroscience,Signal transduction,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extract from rat brain, rat hippocampus and mouse brain using CD56(NCAM) Antibody.
 | | | |
Информация для заказа |
Наименование: NCAM1 Antibody.