MBP AntibodyСпецификация| Объем | 100 мкл | | Синонимы | MGC99675 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P02686 | | Иммуноген | Peptide sequence around aa.291~295(G-G-R-D-S | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.<br/><br/>Pribyl T.M., Campagnoni C.W., Kampf K. Proc. Natl. Acad. Sci. U.S.A. 90:10695-10699(1993) <br/>Nye S.H., Pelfrey C.M., Burkwit J.J. Mol. Immunol. 32:1131-1141(1995) | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Neuroscience,Tags & Cell Markers | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extract from Rat brain, Mouse brain and Rat hippocampus Tissue using MBP Antibody
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Наименование: MBP Antibody.