MARC1 AntibodyСпецификация| Объем | 50 мкл | | Синонимы | mitochondrial amidoxime reducing component 1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q5VT66 | | Иммуноген | Synthetic peptide of human MARC1 | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB, IHC,ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 | | Примечание | MOSC1 (MOCO sulphurase C-terminal domain containing 1), also known as MARC1, is a 337 amino acid mitochondrial protein that is thought to function as an oxidoreductase. Existing as three alternatively spliced isoforms, MOSC1 contains one MOSC domain and binds molybdenum as a cofactor. The gene encoding MOSC1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Cancer,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA200203(MARC1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ?200)
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA200203(MARC1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ?200)
 | Gel: 10%SDS-PAGE, Lysate: 40 ?g, Lane: Human normal liver tissue, Primary antibody: CSB-PA200203(MARC1 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
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