| Объем | 100 мкл |
| Синонимы | EC 1.14.11.-, JMJ2B, Jumonji domain containing protein 2B, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O94953 |
| Иммуноген | Synthesized peptide derived from C-terminal of human JHD3B. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, IHC,IHC:1:50-1:100 |
| Примечание | Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.<br/><br/>Nagase T., DNA Res. 5:355-364(1998).<br/>Nakajima D., DNA Res. 9:99-106(2002).<br/>Grimwood J., Nature 428:529-535(2004). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using JHD3B antibody.
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Наименование: KDM4B Antibody.