KCNQ5 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Potassium voltage-gated channel subfamily KQT member 5, Voltage-gated potassium channel subunit Kv7.5, Potassium channel subunit alpha KvLQT5, KQT-like 5, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9NR82 | | Иммуноген | Synthesized peptide derived from internal of human KCNQ5. | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Probably important in the regulation of neuronal excitability. Associates with KCNQ3 to form a potassium channel which contributes to M-type current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons. May contribute, with other potassium channels, to the molecular diversity of a heterogeneous population of M-channels, varying in kinetic and pharmacological properties, which underlie this physiologically important current. Insensitive to tetraethylammonium, but inhibited by barium, linopirdine and XE991. Activated by niflumic acid and the anticonvulsant retigabine. Muscarine suppresses KCNQ5 current in Xenopus oocytes in which cloned KCNQ5 channels were coexpressed with M1 muscarinic receptors.<br/><br/>Lerche C., J. Biol. Chem. 275:22395-22400(2000).<br/>Mungall A.J., Nature 425:805-811(2003).<br/>Schroeder B.C., J. Biol. Chem. 275:24089-24095(2000).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Neuroscience | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Jurkat cells, using KCNQ5 antibody.
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Наименование: KCNQ5 Antibody.