| Объем | 100 мкг |
| Синонимы | Transcriptional regulator Kaiso (Zinc finger and BTB domain-containing protein 33), ZBTB33, KAISO ZNF348 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q86T24 |
| Иммуноген | Recombinant Human Transcriptional regulator Kaiso protein (113-228AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA |
| Примечание | Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2. Represses expression of MMP7 in conjunction with transcriptional corepressors CBFA2T3, CBFA2T2 and RUNX1T1 (PubMed:23251453). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | HRP |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Transcriptional regulator Kaiso |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: ZBTB33 Antibody, HRP conjugated.