IRF4 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | interferon regulatory factor 4, LSIRF, lymphocyte-specific interferon regulatory factor, multiple myeloma oncogene 1, MUM1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q15306 | | Иммуноген | Synthesized peptide derived from internal of human IRF4. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes By similarity.<br/><br/>Grossman A., Genomics 37:229-233(1996).<br/>Iida S., Nat. Genet. 17:226-230(1997).<br/>Mungall A.J., Nature 425:805-811(2003). | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Tags & Cell Markers | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HeLa cells and Jurkat cells, using IRF4 antibody.
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Наименование: IRF4 Antibody.