| Объем | 50 мкл |
| Синонимы | Interleukin-1 receptor type 2 (IL-1R-2) (IL-1RT-2) (IL-1RT2) (CD121 antigen-like family member B) (CDw121b) (IL-1 type II receptor) (Interleukin-1 receptor beta) (IL-1R-beta) (Interleukin-1 receptor type II) (CD antigen CD121b) [Cleaved into: Interleukin-1 receptor type 2, membrane form (mIL-1R2) (mIL-1RII), Interleukin-1 receptor type 2, soluble form (sIL-1R2) (sIL-1RII)], IL1R2, IL1RB |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P27930 |
| Иммуноген | Recombinant Human Interleukin-1 receptor type 2 protein (20-320AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, Recommended dilution: WB:1:200-1:1000 |
| Примечание | Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity, this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Cardiovascular, Immunology, Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: Interleukin-1 receptor type 2 antibody at 3µg/ml + Mouse kidney tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 46, 34 kDa
Observed band size: 46 kDa
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Наименование: IL1R2 Antibody.