IL17RC AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Interleukin-17 receptor C, IL-17 receptor C, IL-17RC, Interleukin-17 receptor-like protein, IL-17RL | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q8NAC3 | | Иммуноген | Synthesized peptide derived from internal of human IL17RC. | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.<br/><br/>Gray A.M., Genome Res. 13:2265-2270(2003).<br/>Gibbs R.A., Nature 440:1194-1198(2006).<br/>Henzel W.J., Protein Sci. 13:2819-2824(2004).<br/><br/> <br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Immunology | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HeLa, HepG2 and HuvEc cells, using IL17RC antibody.
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Наименование: IL17RC Antibody.