| Объем | 100 мкл |
| Синонимы | Tumor necrosis factor receptor superfamily member 10A [Precursor], Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAIL-R1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | O00220 |
| Иммуноген | Synthesized peptide derived from C-terminal of human TR10A. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.<br/><br/>Pan G., Science 276:111-113(1997).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/>Chaudhary P.M., Immunity 7:821-830(1997).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cardiovascular,Cell biology,Immunology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from K562 cells, COS-7 cells and RAW264.7 cells, using TR10A antibody.
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Наименование: TNFRSF10A Antibody.