| Объем | 100 мкл |
| Синонимы | BA2R, CCG1, Cell cycle gene 1 protein, EC 2.7.11.1, P250 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P21675 |
| Иммуноген | Synthesized peptide derived from internal of human TAF1. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, IHC,IHC:1:50-1:100 |
| Примечание | Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Exhibits histone acetyltransferase activity towards histones H3 and H4.<br/><br/>Sekiguchi T., Mol. Cell. Biol. 11:3317-3325(1991).<br/>Ruppert S., Nature 362:175-179(1993).<br/>Nolte D., Proc. Natl. Acad. Sci. U.S.A. 100:10347-10352(2003).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TAF1 antibody.
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Наименование: TAF1 Antibody.