Sort1 Antibody, Biotin conjugated

Спецификация

Объем	100 мкг
Синонимы	Sortilin (Glycoprotein 110) (Gp110) (Neurotensin receptor 3) (NTR3), Sort1
Клональность	Polyclonal Antibody
Организм	Rat
uniprot	O54861
Иммуноген	Recombinant Rat Sortilin protein (610-754AA)
Источник	Rabbit
Видовая специфичность	Rat
Применение	ELISA
Примечание	Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Biotin
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Области исследований	Neuroscience, Cancer, Cardiovascular, Metabolism
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкг
	Кат. номер:	CSB-PA022412LD01RA
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Sort1 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке).