| Объем | 100 мкл |
| Синонимы | C1orf16, EST1C, KIAA0250, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q92540 |
| Иммуноген | Synthesized peptide derived from internal of human SMG7. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 |
| Примечание | Plays a role in nonsense-mediated mRNA decay. Recruits UPF1 to cytoplasmic mRNA decay bodies. Together with SMG5 is thought to provide a link to the mRNA degradation machinery involving exonucleolytic pathways, and to serve as an adapter for UPF1 to protein phosphatase 2A (PP2A), thereby triggering UPF1 dephosphorylation.<br/><br/>Ohnishi T., Mol. Cell 12:1187-1200(2003).<br/>Nagase T., DNA Res. 3:321-329(1996).<br/>Nakajima D., DNA Res. 9:99-106(2002).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HeLa cells, Jurkat cells, 293 cells and HUVEC cells, using SMG7 antibody.
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Immunofluorescence analysis of HepG2 cells, using SMG7 antibody.
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Наименование: SMG7 Antibody.