RUNX1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | CBFA2, EVI-1, AMLCR1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q01196 | | Иммуноген | Peptide sequence around aa.6~10(D-A-S-T-S) derived from Human AML1(RUNX1). | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The a subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits MYST4-dependent transcriptional activation.<br/><br/>Mao S., Frank R.C., Zhang J., Miyazaki Y., Nimer S.D.Mol. Cell. Biol. 19:3635-3644(1999)<br/> Pelletier N., Champagne N., Stifani S., Yang X.-J. Oncogene 21:2729-2740(2002) <br/>Cho J.-Y., Akbarali Y., Zerbini L.F., Gu X., Boltax J., Wang Y., Oettgen P., Zhang D.-E., Libermann T.A.J. Biol. Chem. 279:19512-19522(2004) | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Cancer,Developmental biology,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extract from P19, Hela and 293 cells using AML1(RUNX1) Antibody
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Наименование: RUNX1 Antibody.