| Объем | 100 мкл |
| Синонимы | C-RAF, C-Raf, CRAF |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P04049 |
| Иммуноген | Peptide sequence around aa.336~340 (R-D-S-S-Y) derived from Human RAF. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:200 |
| Примечание | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3.<br/><br/>Adams DG,et al. (2005)J Biol Chem. 280(52):42644-54.<br/>Miura S, et al. (2003) Biochem Biophys Res Commun. 306(4):924-9.<br/>Noser JA,et al.(2007)Mol Ther.15(8):1531-6.<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
| Области исследований | Cancer,Cell biology,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells using Raf1(Ab-338) Antibody and the same antibody preincubated with blocking peptide.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Raf1(Ab-338) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Наименование: RAF1 (Ab-338) Antibody.