PTPRJ AntibodyСпецификация| Объем | 50 мкл | | Синонимы | Protein tyrosine phosphatase, receptor type, J | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q12913 | | Иммуноген | Synthetic peptide of human PTPRJ | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, IHC,ELISA:1:1000-1:5000, IHC:1:25-1:100 | | Примечание | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA438177(PTPRJ Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Наименование: PTPRJ Antibody.