PTGS1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | COX3, PCOX1, CYCLOOXYGENASE 1, PARTIAL COX1 PROTEINS, PGHS1 CYCLOOXYGENASE 3 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P23219 | | Иммуноген | Synthesized peptide derived from human COX1. | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.<br/><br/>Lawrence M. Szewczuk, J. Biol. Chem., May 2004, 279: 22727 - 22737.<br/>Syed R. Baber, Am J Physiol Heart Circ Physiol, Oct 2005, 289: H1476 - H1487.<br/>Subhashini Chandrasekharan, J. Lipid Res., Dec 2005, 46: 2636 - 2648.<br/>K. Trent Moreland, J. Pharmacol. Exp. T | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cancer,Cardiovascular,Immunology,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human brain tissue using COX1 antibody.
 | Western blot analysis of extracts from HuvEc cells, using COX1 antibody.
 | Western blot analysis of extracts from HuvEc cells (Lane 2), using Cox1 antiobdy. The lane on the left is treated with systhesized peptide.
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Наименование: PTGS1 Antibody.