| Объем | 100 мкл |
| Синонимы | TGF-beta-inhibited membrane-associated protein, hTIMAP, CAAX box protein TIMAP, Ankyrin repeat domain-containing protein 4, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q96T49 |
| Иммуноген | Synthesized peptide derived from internal of human PPP1R16B. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells.<br/><br/>Cao W., Am. J. Physiol. 283:C327-C337(2002).<br/>Nagase T., DNA Res. 5:355-364(1998).<br/>Nakajima D., DNA Res. 9:99-106(2002).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from mouse brain cells, using PPP1R16B antibody.
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Наименование: PPP1R16B Antibody.