GAD2 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Glutamate decarboxylase 2, EC 4.1.1.15, Glutamate decarboxylase 65 kDa isoform, GAD-65, 65 kDa glutamic acid decarboxylase | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q4G154 | | Иммуноген | Synthesized peptide derived from human GAD1/GAD2. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.<br/><br/>JB Travers, Chem Senses, Feb 2007, 32: 129 - 137.<br/>Rita Sulahian, Nucleic Acids Res., Mar 2006, 34: 1351 - 1357.<br/>Andrea Pillai, Development, Jan 2007, 134: 357 - 366.<br/>Dmytro P. Yevtushenko, J. Exp. Bot., Aug 2003, 54: 2001 - 2002.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Others | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from mouse brain cells, using GAD1/2 antibody.
 | Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using GAD1/2 antibody.
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Наименование: GAD2 Antibody.