Phospho-RAF1 (Ser259) Antibody

Спецификация

Объем	100 мкл
Синонимы	C-RAF, C-Raf, CRAF
Клональность	Polyclonal Antibody
Организм	Human
uniprot	P04049
Иммуноген	Peptide sequence around phosphorylation site of serine 259 (S-T-S(p)-T-P) derived from Human Raf1.
Источник	Rabbit
Видовая специфичность	Human, Mouse, Rat
Применение	ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100
Примечание	<p>Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Part of the Ras-dependent signaling pathway from receptors to the nucleus. Protects cells from apoptosis mediated by STK3. <br /><br />Dougherty M K, et al. (2005) Mol Cell. 17(2): 215-224. <br />Hekman M, et al. (2005) FEBS Lett. 579(2): 464-468. <br />Avruch J,et al. (1994) Trends Biochem. Sci. 19, 279-283. <br />Chong H, et al. (2001) EMBO J. 20, 3716-3727. <br />King A J, et al. (1998) Nature. 396:180-183.</p>
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Non-conjugated
Буффер	Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Форма	liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Абревеатура	Phospho-Ser259
Области исследований	Cancer,Cell biology,Metabolism,Signal transduction
Ссылка на страницу на сайте производителя	ссылка
Western blot analysis of extracts from 293 and MDA cells untreated or treated with PMA using Raf1(Phospho-Ser259) Antibody.
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Raf1(Phospho-Ser259) Antibody.

Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкл
	Кат. номер:	CSB-PA291059
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Phospho-RAF1 (Ser259) Antibody. Примечание: дополнительная информация (на английском языке).