| Объем | 100 мкл |
| Синонимы | Trk-B, NTRK2, GP145-TrkB, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q16620 |
| Иммуноген | Peptide sequence around phosphorylation site of tyrosine 706/tyrosine 707 (T-D-Y(p)-Y(p)-R-V)derived from Human Trk B. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, IHC,IHC:1:50-1:100 |
| Примечание | <p>Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.<br/><br/>Nakagawara A., Genomics 25:538-546(1995).<br />Shelton D.L., J. Neurosci. 15:477-491(1995).<br />Stoilov P., Biochem. Biophys. Res. Commun. 290:1054-1065(2002).</p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Tyr706/Tyr707 |
| Области исследований | Others |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemical analysis of paraffin-embedded human brain tissue using Trk B (Phospho-Tyr706/Tyr707) antibody (left)or the same antibody preincubated with blocking peptide (right).
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Наименование: Phospho-NTRK2 (Tyr706/Tyr707) Antibody.