| Объем | 100 мкл |
| Синонимы | Myocyte enhancer factor 2C, Myocyte-specific enhancer factor 2C, Similar to MADS box transcription enhancer factor 2 polypeptide C, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q06413 |
| Иммуноген | Peptide sequence around phosphorylation site of Serine 396(P-V-S(p)-P-P) derived from Human MEF2C. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 |
| Примечание | <p>MEF2C transcription factor of the MADS family which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. May be involved in myogenesis, neurogenesis and in the development of cortical architecture. Three splice-variant isoforms have been described. <br/><br/>Leifer D., Proc. Natl. Acad. Sci. U.S.A. 90:1546-1550(1993).<br />McDermott J.C., Mol. Cell. Biol. 13:2564-2577(1993).<br />Wang A.H., Mol. Cell. Biol. 19:7816-7827(1999).<br /></p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Ser396 |
| Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Cardiovascular,Signal transduction,Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from cos-7 cells (Lane 2), using MEF2C (Phospho-Ser396) Antibody. The lane on the left is treated with antigen-specific peptide.
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Immunohistochemical analysis of paraffin-embedded human brain tissue using MEF2C (Phospho-Ser396) antibody (left)or the same antibody preincubated with blocking peptide (right).
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Наименование: Phospho-MEF2C (Ser396) Antibody.