| Объем | 100 мкл |
| Синонимы | HTATIP, TI60, Tat-interactive protein-60, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q92993 |
| Иммуноген | Peptide sequence around phosphorylation site of Serine 90(P-G-S(p)-P-E) derived from Human Tip60. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, IHC,IHC:1:50-1:100 |
| Примечание | <p>The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.<br/><br/>Kamine J., Virology 216:357-366(1996).<br />Sheridan A.M., Mol. Cell. Biol. 21:4470-4481(2001).<br />Legube G., Gene 310:161-168(2003).<br /></p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Ser90 |
| Области исследований | Epigenetics and Nuclear Signaling,Immunology,Microbiology |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemical analysis of paraffin-embedded human brain tissue using Tip60 (Phospho-Ser90) antibody (left)or the same antibody preincubated with blocking peptide (right).
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Наименование: Phospho-KAT5 (Ser90) Antibody.