| Объем | 100 мкл |
| Синонимы | GRIA2, GluR-2, GluR-B, GluR-K2, AMPA 2 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P42262 |
| Иммуноген | Peptide sequence around phosphorylation site of serine 880 (I-E-S(p)-V-K) derived from Human Glutamate receptor 2. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:1000 |
| Примечание | <p>Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. <br /><br />Cull-Candy, S. et al. (2006) Curr. Opin. Neurobiol. 16, 288-297. <br />Hanley JG, et al. (2002) Neuron. 34(1): 53-67</p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Ser880 |
| Области исследований | Neuroscience |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from mouse brain tissue using Glutamate receptor 2(Precursor)(phospho-Ser880) antibody(Lane 2) and the same antibody preincubated with blocking peptide(Lane1).
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Наименование: Phospho-GRIA2 (Ser880) Antibody.