PDGFRB (Ab-751) AntibodyСпецификация| Объем | 100 мкл | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P09619 | | Иммуноген | Peptide sequence around aa.749~753 (V-D-Y-V-P) derived from Human PDGFRb. | | Источник | Rabbit | | Видовая специфичность | Human, Rat | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | <p>PDGF Receptor b encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor a and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. <br /><br />Lederle W, et al. (2006) Am J Pathol , 169(5): 1767-1783. <br />Vignais ML, et al. (1999) Mol Cell Biol, 19(5): 3727-3735. <br />Herrlich A, et al. (1998) Proc Natl Acad Sci U S A, 95(15): 8985-8990. <br />Heuchel R, et al. (1999) Proc Natl Acad Sci U S A, 96(20): 11410-11415.</p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Cancer,Cardiovascular,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HepG2 cells using PDGF Receptor b(Ab-751) Antibody.
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Наименование: PDGFRB (Ab-751) Antibody.