| Объем | 100 мкл |
| Синонимы | Early response protein NAK1, GFRP, GFRP1, HMR, N10 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P22736 |
| Иммуноген | Synthesized non-phosphopeptide derived from human Nuclear Receptor NR4A1 around the phosphorylation site of serine 351 (L-P-S(p)-K-P). |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' By similarity. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.<br/><br/>Nakai A., Mol. Endocrinol. 4:1438-1443(1990).<br/>Chang C., J. Steroid Biochem. 34:391-395(1989).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using Nuclear Receptor NR4A1 (Ab-351) antibody.
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Western blot analysis of extracts from COS-7 cells, using Nuclear Receptor NR4A1 (Ab-351) antibody.
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Western blot analysis of extracts from HepG2 cells (Lane 2), using Nuclear Receptor NR4A1 (Ab-351) antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: NR4A1 (Ab-351) Antibody.