| Объем | 100 мкг |
| Синонимы | Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Nuclear receptor subfamily 1 group H member 4) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14), NR1H4, BAR FXR HRR1 RIP14 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q96RI1 |
| Иммуноген | Recombinant Human Bile acid receptor protein (1-476AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200 |
| Примечание | Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Области исследований | Epigenetics and Nuclear Signaling, Cancer, Metabolism, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: Bile acid receptor antibody at 2µg/ml + Mouse stomach tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 56, 49, 55 kDa
Observed band size: 56 kDa
 |
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA839406LA01HU at dilution of 1:100
 |
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA839406LA01HU at dilution of 1:100
 |
Western Blot
Positive WB detected in: HEK293 whole cell lysate
All lanes: NR1H4 antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 56, 55, 49 kDa
Observed band size: 56 kDa
 |
| | |
Наименование: NR1H4 Antibody.