NFKB2 (Ab-866) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | DNA-binding factor KBF2, H2TF1, Lymphocyte translocation chromosome 10, Lyt10, NFKB2 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q00653 | | Иммуноген | Peptide sequence around aa.864~868 (E-D-S-A-Y) derived from Human NFkB-p100. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC, IF,WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200 | | Примечание | <p>NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth. <br /><br />Qu Z, et al. (2004) J Biol Chem. 279(43): 44563-44572. <br />Xiao G, et al. (2001) Mol Cell. 7(2): 401-409. <br />Baeuerle P A, et al. (1994) Annu Rev Immunol. 12:141-179. <br />Baeuerle P A, et al. (1996) Cell 87:13-20. <br />Haskill S, et al. (1991) Cell 65:1281-1289. <br /> ,</p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HT29 cells using NFkB-p100(Ab-866) Antibody.
 | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using NFkB-p100(Ab-866) Antibody(left) or the same antibody preincubated with blocking peptide(right).
 | Immunofluorescence staining of methanol-fixed Hela cells using NFkB-p100(Ab-866) Antibody.
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Наименование: NFKB2 (Ab-866) Antibody.