MAPK14 (Ab-182) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | MAPK2, MAPKAPK-2, MAPKAPK2 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q16539 | | Иммуноген | Peptide sequence around aa. 180~184 (T-G-Y-V-A) derived from Human P38 MAPK. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.<br/><br/>Ming Zheng, et al.(2005) The FASEB Journal. 19: 109-111<br/>Bernt van den et al.(2001) Blink Immunology, 166: 582-587<br/>Arshad Rahman, et al. (2004) Am J Physiol Lung Cell Mol Physiol 287: L1017-L1024<br/>Osamu Yoshino, et al. (2003) Endocrinology & Metabolism Vol. 88: 2236-2241<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Cancer,Immunology,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from 293 and Hela cells using P38 MAPK(Ab-182) Antibody.
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Наименование: MAPK14 (Ab-182) Antibody.