| Объем | 50 мкг |
| Синонимы | Protease LasA (EC 3.4.24.-) (Staphylolytic protease), lasA |
| Клональность | Polyclonal Antibody |
| Организм | Pseudomonas aeruginosa |
| uniprot | P14789 |
| Иммуноген | Recombinant Pseudomonas aeruginosa Protease LasA protein (237-418AA) |
| Источник | Rabbit |
| Видовая специфичность | Pseudomonas aeruginosa |
| Применение | ELISA |
| Примечание | Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly-Gly-|-X substrates where X is Ala or Gly (PubMed:11179971). Enhances the elastolytic but not proteolytic activity of elastase (lasB) and elastolytic activity of other proteases (PubMed:2110137). Degradation of host elastin is likely to contribute to the pathogenicity of P.aeruginosa. While either His-317 or His-356 can abstract a proton in the hydrolysis reaction, the same residue performs both functions in a given catalytic cycle, with the other stabilizing the catalytic intermediate (PubMed:20026068). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Области исследований | Others |
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