ITPR2 AntibodyСпецификация| Объем | 50 мкл | | Синонимы | inositol 1,4,5-trisphosphate receptor, type 2 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q14571 | | Иммуноген | Synthetic peptide of human ITPR2 | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, IHC,ELISA:1:2000-1:10000, IHC:1:50-1:200 | | Примечание | Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Cancer,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA247118(ITPR2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Наименование: ITPR2 Antibody.