| Объем | 100 мкл |
| Синонимы | Intraflagellar transport protein 57 homolog (Dermal papilla-derived protein 8) (Estrogen-related receptor beta-like protein 1) (HIP1-interacting protein) (MHS4R2), IFT57, DERP8 ESRRBL1 HIPPI |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9NWB7 |
| Иммуноген | Recombinant Human Intraflagellar transport protein 57 homolog protein (170-429AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200 |
| Примечание | Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Neuroscience |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: IFT57 antibody at 2µg/ml + Mouse lung tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 49 kDa
Observed band size: 49 kDa
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Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA865156ESR2HU at dilution of 1:100
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Наименование: IFT57 Antibody.