HARS AntibodyСпецификация| Объем | 100 мкл | | Синонимы | EC 6.1.1.21, HRS, HisRS, histidine translase, histidine-tRNA ligase | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P12081 | | Иммуноген | Synthesized peptide derived from C-terminal of human HARS. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 | | Примечание | Defects in HARS are a cause of Usher syndrome type 3B (USH3B). USH3B is a syndrome characterized by progressive vision and hearing loss during early childhood. Some patients have the so-called 'Charles Bonnet syndrome,' involving decreased visual acuity and vivid visual hallucinations. USH is a genetically heterogeneous condition characterized by the association of retinitis pigmentosa with sensorineural deafness. Age at onset and differences in auditory and vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndrome type 2 (USH2) and Usher syndrome type 3 (USH3). USH3 is characterized by postlingual, progressive hearing loss, variable vestibular dysfunction, and onset of retinitis pigmentosa symptoms, including nyctalopia, constriction of the visual fields, and loss of central visual acuity, usually by the second decade of life. Belongs to the class-II aminoacyl-tRNA synthetase family.<br/><br/>Raben N., Nucleic Acids Res. 20:1075-1081(1992).<br/>Tsui F.W.L., Nucleic Acids Res. 15:3349-3367(1987).<br/>Tsui H.W., Gene 131:201-208(1993).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling,Immunology | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HeLa cells, using HARS antibody.
 | Immunofluorescence analysis of HepG2 ells, using HARS antibody.
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Наименование: HARS Antibody.