FOXK1 AntibodyСпецификация| Объем | 50 мкл | | Синонимы | forkhead box K1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P85037 | | Иммуноген | Synthetic peptide of human FOXK1 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, IHC,ELISA:1:2000-1:5000, IHC:1:25-1:100 | | Примечание | The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. In skeletal muscles, undifferentiated myogenic stem cells (satellite cells) can mobilize to regenerate myofibers in response to injury. FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Epigenetics and Nuclear Signaling | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA275426(FOXK1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Наименование: FOXK1 Antibody.