| Объем | 50 мкл |
| Синонимы | F-box only protein 7, FBXO7, FBX7 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9Y3I1 |
| Иммуноген | Recombinant Human F-box only protein 7 protein (353-522AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
| Примечание | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5. Plays a role downstream of PINK1 in the clearance of damaged mitochondria via selective autophagy (mitophagy) by targeting PARK2 to dysfunctional depolarized mitochondria. Promotes MFN1 ubiquitination. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Абревеатура | F-box only protein 7 |
| Области исследований | Epigenetics and Nuclear Signaling, Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: FBXO7 antibody at 3.97µg/ml
Lane 1: Mouse gonadal tissue
Lane 2: Jurkat whole cell lysate
Lane 3: 293T whole cell lysate
Lane 4: PC-3 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 59, 50, 46 kDa
Observed band size: 59 kDa
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Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA667562ESR2HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA667562ESR2HU at dilution of 1:100
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Наименование: FBXO7 Antibody.