| Объем | 100 мкл |
| Синонимы | dimethylglycine dehydrogenase, mitochondrial, EC 1.5.99.2, M2GD, ME2GLYDH |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9UI17 |
| Иммуноген | Synthesized peptide derived from C-terminal of human DMGDH. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants.<br/><br/>Binzak B.A., Mol. Genet. Metab. 69:181-187(2000). <br/>Binzak B.A., Am. J. Hum. Genet. 68:839-847(2001).<br/>Moolenaar S.H., Clin. Chem. 45:459-464(1999)<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Neuroscience,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HT-29 cells and A549 cells, using DMGDH antibody.
 |
| | |
Наименование: DMGDH Antibody.