| Объем | 50 мкл |
| Синонимы | Probable ATP-dependent RNA helicase DDX20 (EC 3.6.4.13) (Component of gems 3) (DEAD box protein 20) (DEAD box protein DP 103) (Gemin-3), DDX20, DP103 GEMIN3 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9UHI6 |
| Иммуноген | Recombinant Human Probable ATP-dependent RNA helicase DDX20 protein (25-280AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200 |
| Примечание | The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Абревеатура | Probable ATP-dependent RNA helicase DDX20 |
| Области исследований | Epigenetics and Nuclear Signaling, Neuroscience, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: DDX20antibody at 1.91µg/ml
Lane 1: 293T whole cell lysate
Lane 2: HepG2 whole cell lysate
Lane 3: Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 93, 15 kDa
Observed band size: 93 kDa
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Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA890695DSR2HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA890695DSR2HU at dilution of 1:100
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Наименование: DDX20 Antibody.