CAMK2G/CAMK2B AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Calcium/calmodulin-dependent protein kinase type II gamma chain, EC 2.7.11.17, CaM-kinase II gamma chain, CaM kinase II subunit gamma, CaMK-II subunit gamma | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q13555/Q13554 | | Иммуноген | Synthesized peptide derived from C-terminal of human CaMK2beta/gamma. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca2+ transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca2+ transport and in fast-twitch muscle participates in the control of Ca2+ release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.<br/><br/>Deloukas P., Nature 429:375-381(2004).<br/>Breen M.A., Biochem. Biophys. Res. Commun. 236:473-478(1997).<br/>Tombes R.M., Biochim. Biophys. Acta 1355:281-292(1997). | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Neuroscience,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Jurkat cells and COLO205 cells, using CaMK2?/? antibody.
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Наименование: CAMK2G/CAMK2B Antibody.