CDH23 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | DFNB12, USH1D, cadherin 23 C1, cadherin 23 C2, cadherin related 23 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9H251 | | Иммуноген | Synthesized peptide derived from internal of human CDH23. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, IF,IF:1:100-1:500 | | Примечание | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.<br/><br/>Bolz H., Nat. Genet. 27:108-112(2001).<br/>Clark H.F., Genome Res. 13:2265-2270(2003).<br/>Bork J.M., Am. J. Hum. Genet. 68:26-37(2001).<br/> <br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Neuroscience,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Immunofluorescence analysis of HeLa cells, using CDH23 antibody.
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Наименование: CDH23 Antibody.