| Объем | 100 мкл |
| Синонимы | B-RAF, B-RAF proto-oncogene serine/threonine-protein kinase, B-Raf proto-oncogene serine/threonine-protein kinase, BRAF, BRAF1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P15056 |
| Иммуноген | Synthesized non-phosphopeptide derived from human B-RAF around the phosphorylation site of serine 446 (R-D-S(p)-S-D). |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Phosphorylates MAP2K1, and thereby contributes to the MAP kinase signal transduction pathway.<br/><br/>Stephens R.M., Mol. Cell. Biol. 12:3733-3742(1992).<br/>Albert S., Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.<br/>Hillier L.W., Nature 424:157-164(2003)<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cancer,Cell biology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells, treated with insulin (0.01U/ml, 15mins), using B-RAF (Ab-446) antibody.
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using B-RAF (Ab-446) antibody.
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Наименование: BRAF (Ab-446) Antibody.