| Объем | 100 мкл |
| Синонимы | ATF1, Activating transcription factor 1, Cyclic-AMP-dependent transcription factor ATF-1, TCR-ATF1, TREB36 protein |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P18846 |
| Иммуноген | Synthesized peptide derived from internal of human ATF1. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 |
| Примечание | This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.<br/><br/>Yoshimura T., EMBO J. 9:2537-2542(1990).<br/>Rehfuss R.P., J. Biol. Chem. 266:18431-18434(1991).<br/>Hai T., Genes Dev. 3:2083-2090(1989).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COLO205 cells, HeLa cells and HepG2 cells, using ATF1 antibody.
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Immunofluorescence analysis of HUVEC cells, using ATF1 antibody.
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Наименование: ATF1 Antibody.