YWHAB AntibodyСпецификация| Объем | 100 мкл | | Синонимы | 14-3-3 protein beta/alpha, 1433B, 143B, KCIP-1, Protein 1054 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P31946 | | Иммуноген | Synthesized peptide derived from internal of human 14-3-3 beta. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.<br/><br/>Leffers H., J. Mol. Biol. 231:982-998(1993).<br/>Deloukas P., Nature 414:865-871(2001).<br/>Gevaert K., Nat. Biotechnol. 21:566-569(2003).<br/>Chi A., J. Proteome Res. 5:3135-3144(2006).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Neuroscience,Cell biology,Signal transduction,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HepG2 cells and Jurkat cells, using 14-3-3 ? antibody.
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Наименование: YWHAB Antibody.