| Объем | 100 мкг |
| Синонимы | Protein Vpx (Viral protein X) (X ORF protein), vpx |
| Клональность | Polyclonal Antibody |
| Организм | Human immunodeficiency virus type 2 subtype A |
| uniprot | P18099 |
| Иммуноген | Recombinant Human immunodeficiency virus type 2 subtype A Protein Vpx protein (1-113AA) |
| Источник | Rabbit |
| Видовая специфичность | Human immunodeficiency virus type 2 subtype A |
| Применение | ELISA |
| Примечание | Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by associating with the cellular CUL4A-DDB1 E3 ligase complex through direct interaction with host VPRPB/DCAF-1. This change in the E3 ligase substrate specificity results in the degradation of host SAMHD1. In turn, SAMHD1 depletion allows viral replication in host myeloid cells by preventing SAMHD1-mediated hydrolysis of intracellular dNTPs necessary for reverse transcription. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Protein Vpx |
| Области исследований | Others |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: vpx Antibody.