TWIST1 Antibody, Biotin conjugated

Спецификация

Объем	50 мкг
Синонимы	Twist-related protein 1 (Class A basic helix-loop-helix protein 38) (bHLHa38) (H-twist), TWIST1, BHLHA38 TWIST
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q15672
Иммуноген	Recombinant Human Twist-related protein 1 protein (1-80AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Acts as a transcriptional regulator. Inhibits myogenesis by sequestrating E proteins, inhibiting trans-activation by MEF2, and inhibiting DNA-binding by MYOD1 through physical interaction. This interaction probably involves the basic domains of both proteins. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Regulates cranial suture patterning and fusion. Activates transcription as a heterodimer with E proteins. Regulates gene expression differentially, depending on dimer composition. Homodimers induce expression of FGFR2 and POSTN while heterodimers repress FGFR2 and POSTN expression and induce THBS1 expression. Heterodimerization is also required for osteoblast differentiation. Represses the activity of the circadian transcriptional activator: NPAS2-ARNTL/BMAL1 heterodimer (By similarity).
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Biotin
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	Twist-related protein 1
Области исследований	Epigenetics and Nuclear Signaling, Neuroscience, Cancer, Cardiovascular, Developmental biology, Stem cells
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	50 мкг
	Кат. номер:	CSB-PA025358LD01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: TWIST1 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке).