| Объем | 100 мкл |
| Синонимы | Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2), TP53BP2, ASPP2 BBP |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q13625 |
| Иммуноген | Recombinant Human Apoptosis-stimulating of p53 protein 2 protein (360-600AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, Recommended dilution: WB:1:200-1:1000 |
| Примечание | Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: TP53BP2 antibody at 2µg/ml + Mouse thymus
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 126, 112, 127 kDa
Observed band size: 126 kDa
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Наименование: TP53BP2 Antibody.