| Объем | 100 мкг |
| Синонимы | Probable ubiquitin carboxyl-terminal hydrolase FAF-X (EC 3.4.19.12) (Deubiquitinating enzyme FAF-X) (Fat facets in mammals) (hFAM) (Fat facets protein-related, X-linked) (Ubiquitin thioesterase FAF-X) (Ubiquitin-specific protease 9, X chromosome) (Ubiquitin-specific-processing protease FAF-X), USP9X, DFFRX FAM USP9 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q93008 |
| Иммуноген | Recombinant Human Probable ubiquitin carboxyl-terminal hydrolase FAF-X protein (2360-2484AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA |
| Примечание | Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | HRP |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Probable ubiquitin carboxyl-terminal hydrolase FAF-X |
| Области исследований | Epigenetics and Nuclear Signaling, Neuroscience, Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: USP9X Antibody, HRP conjugated.