| Объем | 100 мкл |
| Синонимы | DNA topoisomerase 2-alpha, EC 5.99.1.3, DNA topoisomerase II, alpha isozyme, TOP2A |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P11388 |
| Иммуноген | Synthesized peptide derived from N-terminal of human TOP2A. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 |
| Примечание | Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes.<br/><br/>Tsai-Pflugfelder M., Proc. Natl. Acad. Sci. U.S.A. 85:7177-7181(1988).<br/>Wasserman R.A., Cancer Res. 53:3591-3596(1993).<br/>Lang A.J., Gene 221:255-266(1998). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HT-29 cells, using TOP2A antibody.
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Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using TOP2A antibody.
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Immunofluorescence analysis of A549 cells, using TOP2A antibody.
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Наименование: TOP2A Antibody.