TOP2B AntibodyСпецификация| Объем | 100 мкл | | Синонимы | DNA topoisomerase II, beta isozyme, EC 5.99.1.3, TP2B, TOP2B | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q02880 | | Иммуноген | Synthesized peptide derived from Internal of human topoisomerase II beta. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Indirectly involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.<br/><br/>Ren篓 M. Linka, Nucleic Acids Res., May 2007, 10.1093.<br/>John R. Jenkins, Nucleic Acids Res., Nov 1992, 20: 5587 - 5592. <br/>Kathryn L. Gilroy, Nucleic Acids Res., Mar 2006, 34: 1597 - 1607.<br/>Sophie Dereuddre, Cancer Res., Oct 1997, 57: 4301 - 4308.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling,Cancer | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Topoisomerase II ? antibody.
 | Western blot analysis of extracts from Jurkat cells, using Topoisomerase II ? antibody.
 | Western blot analysis of extracts from K562 cells (Lane 2), using TOP2B antiobdy. The lane on the left is treated with synthesized peptide.
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Наименование: TOP2B Antibody.